BDBM50436058 CHEMBL254381::PNU-74654::US9738628, Compound PNU-74654

SMILES Cc1ccc(\C=N\NC(=O)c2ccccc2Oc2ccccc2)o1

InChI Key InChIKey=JJEDWBQZCRESJL-DEDYPNTBSA-N

Data  3 KI  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50436058   

TargetCatenin beta-1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50436058(CHEMBL254381 | PNU-74654 | US9738628, Compound PNU...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein labeled human wild-type Tcf4 (residues 7-51) interaction after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50436058(CHEMBL254381 | PNU-74654 | US9738628, Compound PNU...)
Affinity DataKd:  450nMAssay Description:Binding affinity to beta catenin ARD (134 to 671 residues) (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCatenin beta-1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50436058(CHEMBL254381 | PNU-74654 | US9738628, Compound PNU...)
Affinity DataKd:  450nMAssay Description:Binding affinity to beta-catenin (134 to 671 residues) (unknown origin) expressed in Escherichia coli BL21 assessed as dissociation constant by isoth...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCatenin beta-1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50436058(CHEMBL254381 | PNU-74654 | US9738628, Compound PNU...)
Affinity DataKd:  450nMAssay Description:Inhibition of Tcf4 binding to beta-catenin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed